MALDI-TDS: A Coherent MALDI Top-Down-Sequencing Approach Applied to the ABRF-Protein Research Group Study 2008
| Type: | Application |
Application Note |
Expression Proteomics, Clinical Proteomics |
| Number: | Technology |
MT-90 |
MALDI-TOF |
| Year | Products |
2008 |
ultraflex III TOF/TOF, PROTEINEER fc, AnchorChip, WARP-LC, BioTools |
| Author | |
A. Resemann, M. Kay, S. Brand, D. Suckau, Bruker Daltonik GmbH, Bremen, Germany |
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| Reference | |
Application Note # MT-90 |
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Abstract |
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In the ABRF-PRG study 2008 [*] the ability to characterize recombinant proteins was challenged. The study asked for analytical capabilities typically required to QC recombinant proteins. We used a Top-Down-LC-MALDI-reISD strategy to ID the protein and to assign C-terminal heterogeneity of RAGE_HUMAN derived proteins |
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