Top-Down Analysis Using the solariX-TD

Technical Note

Expression Proteomics

TN-33

FTMS

2009

solariX-TD

Michael Easterling, Bruker Daltonics, Billerica MA USA

Bruker Daltonics Technical Note TN-33

Abstract

The solariX-TD^TM FTMS represents a turn-key solution for top-down analysis and sets the standard for the detailed investigation of complex biological systems. Superior sensitivity,
resolving power, and mass accuracy when combined
with dissociation techniques such as ECD, ETD, and CID, as well as integration with LC-MS and LC-MS/MS. solariX-TD offers outstanding performance for top-down analysis of biomolecules. In this note, we demonstrate the performance of solariX-TD for the analysis of several proteins where traditional bottom-up protein analysis alone might not be effective.

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