Uncovering hidden secondary metabolites from myxobacteria using high-resolution chromatography and mass spectrometry

Type: Application

Poster

Gen. Pharma & Chemistry, Metabolomics Studies

Number: Technology

ASMS 2010,MP14-340

UHR-TOF

Year Products

2010

maXis

  Author
 

Daniel Krug1, Gabriela Zurek2, Niña Cortina1, Aiko Barsch², Sandy Yates3and Rolf Müller1 1Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS) and Universität des Saarlandes, Saarbrücken, Germany; 2Bruker Daltonik, Bremen, Germany; 3BrukerDaltonics, Fremont, CA

  Reference
 

ASMS 2010,MP14-340

 

Abstract

 

Efficient detection of molecular features in high-resolution LC-MS datasets is a crucial prerequisite for the susequent mining of complex myxobacterial secondary metabolomes using statistical tools.


Data acquired on the UPLC-ESI UHR-TOF platform are well suited for mining the secondary metabolome due to high mass accuracy and resolution combined with a fast scan rate.

 

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