New Generation of GC/High Resolution TOF-MS: APCI/APLI Source for Increased Flexibility

Application Note

LCGC0708

OTOF

2008

micrOTOF

Thomas Arthen-Engeland and Ralf Dunsbach, Bruker Daltonik GmbH, Bremen, Germany

LCGC Europe THEAPPLICATIONSBOOK July 2008

Abstract

TOF mass spectrometers have been widely used in combination with liquid chromatography. These systems can demonstrate a mass resolution of  15000 FWHM and a mass accuracy of 2 ppm. TOF systems that are designed to work with gas
chromatography usually demonstrate a reduced performance. To date, a solution that uses the same TOF-MS on both GC and LC systems, merely by exchanging the chromatographic system, has not existed. Now, the newly developed Bruker Daltonics APCI source allows a micrOTOF, which is basically an LC–TOF-MS, to be coupled with a gas chromatograph. The performance of the micrOTOF, in terms of mass resolution and mass accuracy, is not influenced by the chromatographic system used for separation. Atmospheric pressure laser ionization (APLI) has been described recently as a useful alternative ionization method for certain applications where high selectivity and sensitivity is required.¹ APLI can also be realized with the new Bruker Daltonics source.

Related Products

APLI Source
PAH
micrOTOF II
GC/APCI Source

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