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Bruker Daltonics
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Virtual Slide Integration

Enabling Non-Targeted Molecular Histology: Öffnet internen Link im aktuellen FensterRead more!

 

 

Further Reading

Application Note
MT-91

High Quality MALDI Imaging of Proteins and Peptides in Small Rodent Organ Tissues

Poster
ABRF 2008-V44-M

A New Sensor-Controlled Preparation Technique for MALDI Tissue Imaging

Poster
ABRF 2008 V45-T

Molecular Histology: a New Application for MALDI Tissue Imaging

Application Note
MT-89

Advances in Molecular Histology with the MALDI Molecular Imager

Scientific Paper
IJMM20-2007

Identifying prostate carcinoma by MALDI-Imaging

Application Note
FTMS-37

High Resolution Molecular Imaging of Pharmaceuticals at Therapeutic Levels

Brochure
BDAL 08-2008, LS-34

Brochure ImagePrep

Brochure
LS-42

Expert Opinion - MALDI Molecular Imager

Brochure
LS-41

MALDI Molecular Imaging at the Imaging Congress in Nice, France

Scientific Paper
10.1021/pr8005777

MALDI Imaging Combined with Hierarchical Clustering as a New Tool for the Interpretation of Complex Human Cancers

Technical Note
TN-31

TN-31 - Redefining MALDI-TOF/TOF Performance: ultrafleXtreme

Scientific Paper
10.1007/s00418-008-0469-9

MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology

Application Note
MT-98

Spatially Resolved Tryptic Digest on Tissue using the ImagePrep

Journal Article
GLJ-1112-09

Tissue Imaging Mass Spectrometry - Essential Steps to Molecular Histology at High Resolution

Application Note
MT-103

FAST-SRM: A new Single Reaction Monitoring Method for Fast, Targeted Drug Distribution Testing in Tissue Sections

Scientific Paper
DOI: 10.1002/path.2771

Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity

Scientific Paper
10.1021/ac1029659

Binary Matrix for MALDI Imaging Mass Spectrometry of Phospholipids in Both Ion Modes

Brochure

The new ultrafleXtreme - Beyond Imagination

Multimedia

Virtual Microscopy MALDI Imaging

Flash is required!

This video shows a screen recording of Brukers flexImaging software. It features a MALDI imaging dataset of a rat testis, recorded at 20µm resolution. The dataset is co-registered with a microscopic virtual slide of the same tissue section that was stained with H&E after the MALDI measurement. The video shows how the overlay of microscopic and molecular modality is necessary for a complete understanding of the dataset.

MALDI Imaging of Mouse Pancreatic Cancer

Flash is required!

This video shows a screen recording of Brukers flexImaging software. It features a MALDI imaging dataset of mouse pancreatic cancer, recorded at 50µm spatial resolution on a solariX FTMS. The dataset is co-registered with a microscopic virtual slide of the same tissue section that was stained with H&E after the MALDI measurement. The video shows how the overlay of microscopic and molecular modality is necessary for a complete understanding of the dataset.

Watch a synopsis of a MALDI Imaging Live Demonstration at Bruker Daltonics

Flash is required!

Visualization of the spatial distribution of proteins, drug candidate compounds and biomarkers is a promising tool in the exciting fields of biomarker evaluation and drug development. MALDI-TOF mass spectrometry provides a fast and reliable screening tool for direct analysis from tissue.

 
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