Glycosylation

Glycosylated biomolecules such as proteins and lipids play a fundamental role in many biological processes, such as in cellular recognition and immune response. The characterization of glycosylated structure remains as one of the great challenges in protein characterization on the single protein or on the system wide level. There are increasing numbers of analytical tools available for glycobiology and Bruker continues to innovate in this field, delivering a range of solutions.

Molecular weight determination of glycans or glycopeptides offer initial insights of their structure. Selective glycan fragmentation in the mass spectrometers provides further details that are indispensable to revealing more structural details.