New Tricks to Sequence a Protein

Journal Article

Expression Proteomics

MALDI-TOF

2011

ultrafleXtreme, BioTools, ProteinScape

Anja Resemann, Arndt Asperger and Detlev Suckau

G.I.T. Laboratory Journal 7-8/2011, pp 25–27,

Abstract

Proteins become increasingly important in drug development, prompting for
their detailed analysis and side product characterization in development and
QC. Mass spectrometric Top-Down sequencing (TDS) addresses the key requirement
to assign N- and C-terminal sequences in biologics and biosimilars.
The principles of the new technology are described and related to the classical
Edman-sequencing approach.

Related Products

ultrafleXtreme series
Top-Down Protein Characterization

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