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Species Identification of Clinical Isolates of Anaerobic Bacteria: a Comparison of Two Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Systems
| Type: | Application |
Scientific Paper |
Clinical Proteomics |
| Number: | Technology |
10.1128/JCM.05788-11 |
MALDI-TOF |
| Year | Products |
2011 |
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| Author | |
Ulrik Stenz Justesen1,*, Anette Holm2, Elisa Knudsen1, Line Bisgaard Andersen2, Thøger Gorm Jensen1, Michael Kemp1, Marianne Nielsine Skov1, Bente Gahrn-Hansen1 and Jens Kjølseth Møller2 |
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| Reference | |
Abstract |
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We compared two MALDI-TOF MS systems (Shimadzu/SARAMIS and Bruker) on a collection of consecutive clinically important anaerobic bacteria (n=290). The Bruker system had more correct identifications to the species level (67.2% versus 49.0%), but also more incorrect identifications (7.9% versus 1.4%). The system databases need to be optimized to increase identification levels. However, MALDI-TOF MS in its present version seems to be a fast and inexpensive method for identification of most clinically important anaerobic bacteria.
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